Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642850 | 0.86 | MAOB (0.68) | MAOBNR4A2PARP10MAOASCN9A | |
| SCHEMBL30102056 | 0.86 | MAOB (0.68) | MAOBNR4A2PARP10MAOASCN9A | |
| SCHEMBL15061351 | 0.85 | MAOB (0.59) | MAOBNR4A2PARP10MGLL | |
| SCHEMBL5537147 | 0.83 | LTA4H (0.66) | MAOBMGLL | |
| SCHEMBL1046626 | 0.83 | TAAR1 (0.55) | — | |
| SCHEMBL15061331 | 0.83 | MAOB (0.66) | MAOBMAOA | |
| SCHEMBL5539557 | 0.82 | LTA4H (0.68) | MAOBMGLL | |
| SCHEMBL9431981 | 0.81 | TAAR1 (0.57) | — | |
| SCHEMBL4425903 | 0.81 | MAOB (0.73) | MAOBNR4A2PARP10MAOASCN9A | |
| SCHEMBL565998 | 0.81 | MAOB (1.00) | MAOBNR4A2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476302-B2 | α-ketoamide derivatives useful endothelial lipase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-07-02 | — | — | US | claimed |