Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431992 | 1.00 | NOS2 (0.39) | NOS2NOS1 | |
| SCHEMBL6996772 | 0.82 | — | — | |
| SCHEMBL3935708 | 0.82 | — | — | |
| SCHEMBL19595018 | 0.82 | — | — | |
| SCHEMBL311338 | 0.80 | — | — | |
| SCHEMBL3932444 | 0.77 | — | — | |
| SCHEMBL397148 | 0.77 | — | — | |
| SCHEMBL818572 | 0.75 | NOS2 (0.46) | NOS2NOS1 | |
| SCHEMBL10597539 | 0.75 | NOS2 (0.46) | NOS2NOS1 | |
| SCHEMBL10597549 | 0.75 | NOS2 (0.46) | NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |