⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431992 | 0.80 | NOS2 (0.39) | — | |
| SCHEMBL9431986 | 0.80 | NOS2 (0.39) | — | |
| SCHEMBL5172 | 0.80 | — | — | |
| SCHEMBL5481 | 0.75 | — | — | |
| SCHEMBL5241 | 0.75 | — | — | |
| SCHEMBL3314669 | 0.74 | — | — | |
| SCHEMBL4325 | 0.72 | CYP1A2 (0.40) | — | |
| SCHEMBL5143 | 0.72 | CYP1A2 (0.40) | — | |
| SCHEMBL866288 | 0.72 | CYP1A2 (0.40) | — | |
| SCHEMBL5276 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093390-B2 | Substituted fused [1,2]imidazo[4,5-C] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090005371-A1 | Substituted Fused [1,2]Imidazo[4,5-C] Ring Compounds and Methods | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-01 | — | — | US | disclosed |
| EP-1845986-A2 | SUBSTITUTED FUSED [1,2]IMIDAZO[4,5-C]RING COMPOUNDS AND METHODS | Coley Pharmaceutical Group, Inc. (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006086633-A2 | SUBSTITUTED FUSED [1,2]IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-17 | — | — | WO | disclosed |