Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | F9 | P00740 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829404 | 0.90 | SLC9A1 (0.61) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20509928 | 0.87 | SLC9A1 (0.52) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9432173 | 0.84 | F9 (0.47) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8329863 | 0.81 | HDAC3 (0.51) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9432172 | 0.79 | SLC9A1 (0.42) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL806489 | 0.79 | SLC9A1 (0.58) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5584284 | 0.79 | HDAC3 (0.52) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL721446 | 0.79 | L3MBTL1 (0.57) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15698911 | 0.79 | HDAC3 (0.52) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL829725 | 0.78 | SLC9A1 (0.56) | SLC9A1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |