SCHEMBL9432115

SCHEMBL9432115

CCc1nc(Cl)nc(OC)n1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11936455 0.84 CYP1A2 (0.38) CYP1A2CYP2C19LMNA
SCHEMBL13841377 0.81 KDM4E (0.39) CYP1A2LMNA
SCHEMBL329417 0.78 CYP1A2 (0.52) CYP1A2CYP2C19LMNA
SCHEMBL1317017 0.78 ALDH1A1 (0.50) LMNA
SCHEMBL7400206 0.78 ALDH1A1 (0.41) LMNA
SCHEMBL8795 0.78 CYP1A2 (0.52) CYP1A2LMNA
SCHEMBL9680459 0.76 CYP1A2 (0.33) CYP1A2CYP2C19
SCHEMBL25821973 0.76 GAA (0.42) CYP1A2CYP2C19
SCHEMBL9402313 0.74 POLB (0.43) CYP1A2CYP2C19LMNA
SCHEMBL29838160 0.74 HRH4 (0.41) CYP1A2CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975262-B2 Synthetic mimetics of host defense and uses thereof CELLCEUTIX CORPORATION (US) 2015-03-10 US disclosed
US-5284820-A Herbicidal substituted cycloalkenes BAYER AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed
EP-0355385-B1 SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1993-05-19 EP disclosed
EP-0532948-A1 Substituted cycloalkenes as herbicides BAYER AG (DE) 1993-03-24 EP disclosed
US-5151514-A Triazine substituted herbicides BAYER AKTIENGESELLSCHAFT (DE) 1992-09-29 US disclosed
US-5142060-A Herbicidal substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-5091529-A HERBICIDAL SUBSTITUTED SULPHONYLAMINOAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-5089627-A Chemical intermediates therefor BAYER AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-5085687-A HERBICIDAL SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
US-5021082-A Pre=and postemergent BAYER AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
EP-0419831-A2 Substituted sulfonylaminoazoles BAYER AG (DE) 1991-04-03 EP disclosed
US-4988381-A HERBICIDES, PLANT GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
EP-0384250-A2 Sulfonylated azinyliminoheteroazole, process and intermediates for their preparation and their use as herbicides BAYER AG (DE) 1990-08-29 EP disclosed
EP-0384244-A1 Sulfonylimino-azinyl heteroazoles, method and intermediates for their preparation and their use as herbicides BAYER AG (DE) 1990-08-29 EP disclosed
US-4941912-A Herbicidal substituted sulphonylaminoazoles BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
EP-0355385-A1 Substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones, process and intermediates for their preparation and their use as herbicides BAYER AG (DE) 1990-02-28 EP disclosed
EP-0330959-A2 Substituted sulphonyl amino azoles BAYER AG (DE) 1989-09-06 EP disclosed