Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
| ▸ | TOP2A | P11388 | 14/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897109 | 0.87 | ALDH1A1 (0.63) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9416068 | 0.84 | ALDH1A1 (0.82) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL1387312 | 0.84 | ALDH1A1 (0.82) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9416082 | 0.84 | ALDH1A1 (0.82) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9045944 | 0.83 | ALDH1A1 (0.63) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| Hydrochloric Acid SCHEMBL9416083 | 0.83 | ALDH1A1 (0.80) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| Hydrochloric Acid SCHEMBL8566510 | 0.83 | ALDH1A1 (0.80) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL8699900 | 0.83 | ALDH1A1 (0.71) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| Hydrochloric Acid SCHEMBL8566204 | 0.82 | ALDH1A1 (0.72) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9433042 | 0.82 | TOP1 (0.60) | ALDH1A1POLBCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324735-A | Antimicrobial agent | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0486687-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |