SCHEMBL9432196

SCHEMBL9432196

C1CCCC(C2CSCC[N]2)CCC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7799324 0.89
SCHEMBL5473839 0.73 ALDH1A1 (0.41) NOS1NOS2
SCHEMBL35294 0.69 NOS1 (0.41) NOS1NOS2
SCHEMBL8396522 0.69 NOS1 (0.41) NOS1NOS2
SCHEMBL7853007 0.69 NOS1 (0.41) NOS1NOS2
SCHEMBL7854014 0.69 NOS1 (0.41) NOS1NOS2
SCHEMBL6470302 0.69 NOS1 (0.41) NOS1NOS2
SCHEMBL7853380 0.69 NOS1 (0.41) NOS1NOS2
SCHEMBL8391462 0.69 NOS1 (0.41) NOS1NOS2
SCHEMBL1884259 0.69 NOS1 (0.41) NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5358949-A Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-25 US disclosed
EP-0236140-A2 Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-09 EP disclosed