Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.50 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30173794 | 1.00 | PLOD2 (0.56) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL7543318 | 0.88 | HDAC1 (0.50) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL23792310 | 0.86 | PLOD2 (0.51) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL28522671 | 0.84 | PLOD2 (0.50) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL7075878 | 0.84 | PLOD2 (0.69) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL23992253 | 0.83 | HDAC1 (0.54) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL14073817 | 0.83 | PLOD2 (0.59) | PLOD2HDAC1HDAC8ALDH1A1APP | |
| SCHEMBL15445292 | 0.83 | KMT2A (0.59) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL29020091 | 0.81 | PLOD2 (0.50) | PLOD2HDAC1HDAC8CTNNB1WNT3A | |
| SCHEMBL552724 | 0.81 | PLOD2 (0.61) | PLOD2HDAC1HDAC8CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12157731-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2024-12-03 | — | — | US | disclosed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-12-14 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | PIC Therapeutics, Inc. (US) | 2023-09-12 | — | — | US | disclosed |
| EP-4114529-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| US-20220356178-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2022-11-10 | — | — | US | disclosed |
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |
| US-5352793-A | Sunscreen compounds | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1994-10-04 | — | — | US | disclosed |
| EP-0287603-B1 | SUNSCREEN COMPOSITIONS AND COMPOUNDS FOR USE THEREIN | ICI AUSTRALIA OPERATIONS (AU) | 1993-12-22 | — | — | EP | disclosed |
| EP-0287603-A4 | SUNSCREEN COMPOSITIONS AND COMPOUNDS FOR USE THEREIN | — | 1991-12-27 | — | — | EP | disclosed |
| US-5000946-A | Sunscreen compositions and compounds for use therein | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED, 1 NICHOLSON STREET, MELBOURNE, VICTORIA 3001, AUSTRALIA, A COMPANY OF AUSTRALIA | 1991-03-19 | — | — | US | disclosed |
| EP-0356843-A2 | Process for the preparation of heteroaromatic aldehydes and ketones | BASF Aktiengesellschaft (DE) | 1990-03-07 | — | — | EP | disclosed |
| EP-0287603-A1 | SUNSCREEN COMPOSITIONS AND COMPOUNDS FOR USE THEREIN. | ICI AUSTRALIA OPERATIONS (AU) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988002251-A1 | SUNSCREEN COMPOSITIONS AND COMPOUNDS FOR USE THEREIN | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1988-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399322-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | PLOD2 4577/4885HDAC1 1462/4885HDAC8 1494/4885 |
| US-12157731-B2 | EIF4E inhibitors and uses thereof | EIF4E, EIF4EBP1, EIF4A1 | PLOD2 4577/4885HDAC1 1462/4885HDAC8 1494/4885 |
| US-11753403-B2 | EIF4E inhibitors and uses thereof | EIF4E, EIF4EBP1, EIF4A1 | PLOD2 4577/4885HDAC1 1462/4885HDAC8 1494/4885 |
| US-20220356178-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | PLOD2 4577/4885HDAC1 1462/4885HDAC8 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.