Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434315 | 0.87 | MAPK1 (0.51) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL9434117 | 0.84 | ALDH1A1 (0.49) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL15619314 | 0.80 | MCL1 (0.71) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL1520807 | 0.79 | MCL1 (1.00) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL15697615 | 0.76 | MCL1 (0.76) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL26778431 | 0.76 | MCL1 (0.65) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL17973604 | 0.74 | MCL1 (0.57) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL22908882 | 0.74 | MCL1 (0.67) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL28587713 | 0.73 | MCL1 (0.56) | MCL1MAPK1OGG1ALDH1A1KDM4E | |
| SCHEMBL9433616 | 0.72 | MCL1 (0.60) | MCL1MAPK1OGG1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |