Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645243 | 0.87 | NOS2 (0.40) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL14645245 | 0.87 | NOS2 (0.40) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL14645246 | 0.87 | NOS2 (0.40) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL111220 | 0.85 | NOS2 (0.42) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL111218 | 0.85 | NOS2 (0.42) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL7773882 | 0.85 | NOS2 (0.42) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL111219 | 0.85 | NOS2 (0.42) | ARG1ARG2NOS2NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL28613072 | 0.84 | NOS2 (0.41) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL25177325 | 0.82 | GRIK1 (0.35) | ARG1ARG2NOS2NOS1NOS3 | |
| SCHEMBL21979221 | 0.82 | GRIK1 (0.35) | ARG1ARG2NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298647-A | Aromatic compounds of amide structure derived from aminobenzoic acids, hydroxy-benzoic acids, cinnamic acids, urocanic acids and benzimidazoles, absorbing UVB and/or UVA | ROBERT DOMINIQUE (FR) | 1994-03-29 | — | — | US | disclosed |
| EP-0235064-B1 | AROMATIC COMPOUNDS WITH AMIDE STRUCTURE, DERIVATIVES OF AMINO-BENZOIC ACIDS, HYDROXYBENZOIC ACIDS, CINNAMIC ACIDS, UROCANIC ACIDS AND BENZIMIDAZOLES, ABSORBING UVB AND/OR UVA | Robert, Dominique (FR) | 1992-06-17 | — | — | EP | disclosed |
| EP-0235064-A2 | Aromatic compounds with amide structure, derivatives of amino-benzoic acids, hydroxybenzoic acids, cinnamic acids, urocanic acids and benzimidazoles, absorbing UVB and/or UVA | Robert, Dominique (FR) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987004923-A2 | AROMATIC AMIDES ABSORBING THE U.V. | ROBERT DOMINIQUE | 1987-08-27 | — | — | WO | disclosed |