⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247492 | 0.80 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL24916774 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL30201993 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL14082023 | 0.80 | CCR1 (0.52) | — | |
| SCHEMBL10144469 | 0.78 | KCNH2 (0.54) | — | |
| SCHEMBL91367 | 0.78 | — | — | |
| SCHEMBL2010535 | 0.77 | CCR1 (0.44) | — | |
| SCHEMBL5155 | 0.76 | — | — | |
| SCHEMBL510598 | 0.76 | — | — | |
| SCHEMBL1515200 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513260-B2 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-08-20 | — | — | US | claimed |
| EP-2435420-B1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-04-03 | — | — | EP | claimed |
| US-20120190687-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG | 2012-07-26 | — | — | US | claimed |
| US-20110021539-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | US | claimed |
| WO-2010136145-A1 | PYRAZINYLPYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | WO | claimed |
| EP-1019367-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | claimed |
| WO-1999007672-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-02-18 | — | — | WO | claimed |
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-8513260-B2 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-08-20 | — | — | US | disclosed |
| EP-2435420-B1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-04-03 | — | — | EP | disclosed |
| US-20120190687-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG | 2012-07-26 | — | — | US | disclosed |
| US-20110021539-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | US | disclosed |
| EP-2266973-A1 | Pyrazinylpyrazole | Bayer CropScience AG (DE) | 2010-12-29 | — | — | EP | disclosed |
| WO-2010136145-A1 | PYRAZINYLPYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | WO | disclosed |
| EP-1019367-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999007672-A1 | DERIVATIVES OF 2,5- AND 3,5-DISUBSTITUTED ANILINES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-02-18 | — | — | WO | disclosed |