Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432716 | 0.91 | CACNA1F (0.57) | CACNA1FCACNA1DCACNA1SCACNA1CKDM4E | |
| SCHEMBL9433821 | 0.88 | ALDH1A1 (0.46) | CACNA1DCACNA1BTP53IRAK4KDM4E | |
| SCHEMBL9433669 | 0.87 | ALDH1A1 (0.47) | CACNA1BNPY5RABL1BCRMAPK1 | |
| SCHEMBL9434392 | 0.86 | CACNA1B (0.45) | CACNA1BTP53MAPK1MAPTKDM4E | |
| SCHEMBL9434042 | 0.85 | CACNA1B (0.48) | CACNA1BMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL9433827 | 0.85 | CACNA1B (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B | |
| SCHEMBL9434642 | 0.85 | CACNA1B (0.52) | CACNA1BNPY5R | |
| SCHEMBL9434106 | 0.84 | CACNA1B (0.46) | CACNA1BABL1BCRMAPK1MAPT | |
| SCHEMBL9434084 | 0.83 | CACNA1B (0.61) | CACNA1B | |
| SCHEMBL10564440 | 0.82 | CACNA1F (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |