Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434392 | 0.90 | CACNA1B (0.45) | ALDH1A1SMN1; SMN2NPSR1CACNA1BKMO | |
| SCHEMBL9434042 | 0.89 | CACNA1B (0.48) | ALDH1A1SMN1; SMN2NPSR1CACNA1BKMO | |
| SCHEMBL9433827 | 0.89 | CACNA1B (0.48) | ALDH1A1SMN1; SMN2NPSR1CACNA1BKMO | |
| SCHEMBL9434642 | 0.89 | CACNA1B (0.52) | CACNA1BNPY5R | |
| SCHEMBL9434106 | 0.88 | CACNA1B (0.46) | ALDH1A1SMN1; SMN2NPSR1CACNA1BKMO | |
| SCHEMBL10432258 | 0.88 | GAA (0.48) | ALDH1A1SMN1; SMN2NPSR1KDM4EGAA | |
| SCHEMBL9434755 | 0.87 | CACNA1B (0.45) | ALDH1A1SMN1; SMN2NPSR1CACNA1BKMO | |
| SCHEMBL9433385 | 0.87 | CACNA1F (0.45) | ALDH1A1SMN1; SMN2CACNA1BKDM4EGAA | |
| SCHEMBL9433980 | 0.85 | CACNA1F (0.52) | CACNA1BLMNAMAPTMAPK1KMT2A | |
| SCHEMBL7267531 | 0.84 | KMO (0.52) | ALDH1A1SMN1; SMN2NPSR1CACNA1BKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |