Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432453 | 0.89 | KDM4E (0.49) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9434792 | 0.88 | CACNA1B (0.43) | ALDH1A1MAPTCACNA1CMAPK1CACNA1B | |
| SCHEMBL9434419 | 0.87 | KDM4E (0.49) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9434605 | 0.87 | NR1I2 (0.52) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9434070 | 0.87 | KDM4E (0.47) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9434798 | 0.85 | KMT2A (0.47) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9433816 | 0.85 | CACNA1C (0.46) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL10432690 | 0.84 | HSD17B10 (0.48) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9433913 | 0.83 | CYP2C9 (0.61) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 | |
| SCHEMBL9434515 | 0.82 | PDE1C (0.69) | KDM4EHSD17B10HPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |