Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.61 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434419 | 0.92 | KDM4E (0.49) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9434688 | 0.89 | KDM4E (0.47) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9434014 | 0.89 | KDM4E (0.45) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL10432453 | 0.85 | KDM4E (0.49) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9434798 | 0.84 | KMT2A (0.47) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9434605 | 0.83 | NR1I2 (0.52) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9434070 | 0.83 | KDM4E (0.47) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9433574 | 0.83 | KDM4E (0.47) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 | |
| SCHEMBL9434716 | 0.82 | CACNA1F (0.53) | KDM4ECYP3A4HSD17B10KMT2AALDH1A1 | |
| SCHEMBL29755877 | 0.82 | KDM4E (0.85) | CYP2C9KDM4ECYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |