Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433545 | 0.88 | CACNA1B (0.44) | CACNA1BALDH1A1GAACACNA1CMKNK1 | |
| SCHEMBL9433574 | 0.88 | KDM4E (0.47) | CACNA1BALDH1A1GAACACNA1CMAPT | |
| SCHEMBL9433577 | 0.87 | PKM (0.47) | CACNA1BCACNA1CPKM | |
| SCHEMBL9434851 | 0.86 | KDM4E (0.44) | CACNA1BALDH1A1CACNA1CMKNK1MKNK2 | |
| SCHEMBL9433824 | 0.86 | CACNA1B (0.43) | CACNA1BALDH1A1GAACACNA1CMKNK1 | |
| SCHEMBL9433588 | 0.84 | MAPT (0.42) | CACNA1BALDH1A1GAACACNA1CKMO | |
| SCHEMBL9433754 | 0.84 | GAA (0.44) | CACNA1BALDH1A1GAAMKNK1MKNK2 | |
| SCHEMBL9434815 | 0.84 | CACNA1C (0.44) | CACNA1BALDH1A1GAACACNA1CMAPT | |
| SCHEMBL9433919 | 0.83 | CACNA1B (0.44) | CACNA1BALDH1A1GAAMKNK1MKNK2 | |
| SCHEMBL9434014 | 0.82 | KDM4E (0.45) | CACNA1BALDH1A1GAAMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |