Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.43 |
| ▸ | CASP7 | P55210 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434358 | 0.92 | GAA (0.46) | GAAHPGDNPSR1ALDH1A1MAPK1 | |
| SCHEMBL10432258 | 0.90 | GAA (0.48) | GAAHPGDNPSR1ALDH1A1MAPK1 | |
| SCHEMBL9434716 | 0.89 | CACNA1F (0.53) | GAAHPGDNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9434642 | 0.89 | CACNA1B (0.52) | CACNA1B | |
| SCHEMBL10432716 | 0.88 | CACNA1F (0.57) | GAAHPGDNPSR1ALDH1A1CYP3A4 | |
| SCHEMBL9434208 | 0.88 | GAA (0.46) | CACNA1BGAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL9434188 | 0.88 | POLB (0.50) | CACNA1BGAAHPGDNPSR1ALDH1A1 | |
| SCHEMBL10678279 | 0.87 | CACNA1B (0.55) | CACNA1BSLC6A3 | |
| SCHEMBL9434369 | 0.84 | MAPT (0.63) | MAPK1CYP3A4 | |
| SCHEMBL9434688 | 0.84 | KDM4E (0.47) | GAAHPGDNPSR1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |