Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433913 | 0.89 | CYP2C9 (0.61) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL9434419 | 0.88 | KDM4E (0.49) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL9434169 | 0.88 | CACNA1B (0.41) | KDM4EGAALMNAHTTSMN1; SMN2 | |
| SCHEMBL9434716 | 0.85 | CACNA1F (0.53) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL9433624 | 0.84 | CACNA1B (0.48) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL9434358 | 0.84 | GAA (0.46) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL9434335 | 0.82 | TSHR (0.48) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL10432258 | 0.82 | GAA (0.48) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL10432453 | 0.81 | KDM4E (0.49) | KDM4EHPGDALDH1A1HSD17B10GAA | |
| SCHEMBL9434534 | 0.80 | KDM4E (0.51) | KDM4EHPGDALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |