Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434335 | 0.91 | TSHR (0.48) | HPGDNPSR1TSHRGAACYP3A4 | |
| SCHEMBL9434358 | 0.90 | GAA (0.46) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL10432690 | 0.89 | HSD17B10 (0.48) | HPGDNPSR1TSHRGAACYP3A4 | |
| SCHEMBL9433659 | 0.89 | TSHR (0.46) | HPGDNPSR1TSHRGAACYP3A4 | |
| SCHEMBL9434534 | 0.89 | KDM4E (0.51) | HPGDNPSR1TSHRGAACYP3A4 | |
| SCHEMBL9433624 | 0.89 | CACNA1B (0.48) | HPGDNPSR1GAACYP3A4KDM4E | |
| SCHEMBL9434417 | 0.88 | MAPT (0.45) | CACNA1FCACNA1DCACNA1SCACNA1CABCC1 | |
| SCHEMBL9434055 | 0.87 | GAA (0.45) | HPGDNPSR1TSHRGAACYP3A4 | |
| SCHEMBL9434688 | 0.85 | KDM4E (0.47) | HPGDNPSR1TSHRGAACYP3A4 | |
| SCHEMBL9434419 | 0.84 | KDM4E (0.49) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |