Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 11/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434370 | 0.92 | KDM4E (0.60) | HSD17B10KDM4ECACNA1BCASP1CASP7 | |
| SCHEMBL10432260 | 0.89 | HSD17B10 (0.60) | HSD17B10KDM4ECACNA1BCASP1CASP7 | |
| SCHEMBL9434728 | 0.88 | KDM4E (0.61) | HSD17B10KDM4ECASP1CASP7ADORA3 | |
| SCHEMBL9434633 | 0.88 | CACNA1B (0.59) | CACNA1B | |
| SCHEMBL9434198 | 0.88 | HSD17B10 (0.58) | HSD17B10KDM4ECACNA1BCASP1CASP7 | |
| SCHEMBL9434200 | 0.88 | KDM4E (0.58) | HSD17B10KDM4ECASP1CASP7ADORA3 | |
| SCHEMBL9434216 | 0.88 | HSD17B10 (0.58) | HSD17B10KDM4ECACNA1BCASP1CASP7 | |
| SCHEMBL9433755 | 0.85 | CACNA1F (0.60) | HSD17B10KDM4ECACNA1BCASP1CASP7 | |
| SCHEMBL9434383 | 0.84 | MAPT (0.64) | ADORA3SMN1; SMN2 | |
| SCHEMBL9434702 | 0.84 | KDM4E (0.61) | HSD17B10KDM4ECACNA1BCASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |