Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | CASP1 | P29466 | 4/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434428 | 0.89 | KDM4E (0.61) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9433924 | 0.88 | KDM4E (0.62) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434164 | 0.87 | KDM4E (0.43) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434114 | 0.87 | KDM4E (0.81) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434728 | 0.84 | KDM4E (0.61) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9433631 | 0.84 | HSD17B10 (0.58) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434370 | 0.83 | KDM4E (0.60) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL10432455 | 0.82 | KDM4E (0.64) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL9434343 | 0.82 | KDM4E (0.64) | KDM4EHSD17B10CASP1CASP7ALDH1A1 | |
| SCHEMBL10432260 | 0.81 | HSD17B10 (0.60) | KDM4EHSD17B10CASP1CASP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |