Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.60 |
| ▸ | PRNP | P04156 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372198 | 0.89 | EDNRA (0.61) | EDNRAMAOBMAOADYRK1ACASP3 | |
| SCHEMBL15465845 | 0.87 | EDNRA (0.59) | EDNRAMAPK1NPSR1RXFP1MAOB | |
| SCHEMBL9432904 | 0.82 | EDNRA (0.60) | EDNRAPARP10MAOBMAOAPLAU | |
| SCHEMBL8442498 | 0.82 | ICAM1 (0.61) | EDNRAPRNPTSHRMAPK1PPARG | |
| SCHEMBL9433072 | 0.80 | PRNP (0.81) | PRNPTSHRMAPK1PPARGHTT | |
| SCHEMBL9374477 | 0.79 | DYRK1A (0.56) | EDNRAPRNPTSHRMAPK1PPARG | |
| SCHEMBL19696359 | 0.77 | EDNRA (0.49) | EDNRANPSR1KDM4EALDH1A1 | |
| SCHEMBL23474866 | 0.77 | DYRK1A (0.54) | EDNRAPRNPTSHRMAPK1PPARG | |
| SCHEMBL8021187 | 0.77 | DYRK1A (0.53) | EDNRAPRNPTSHRMAPK1PPARG | |
| SCHEMBL3156910 | 0.77 | ALOX5 (0.58) | EDNRAMAOBMAOACYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |