Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15619321 | 0.84 | MAPK1 (0.56) | MAPK1MCL1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4343748 | 0.82 | ALDH1A1 (0.73) | MAPK1MCL1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9434117 | 0.80 | ALDH1A1 (0.49) | MAPK1MCL1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9434019 | 0.77 | ALDH1A1 (0.46) | MAPK1MCL1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL31370875 | 0.77 | PFKFB3 (0.46) | MAPK1MCL1ALDH1A1KDM4ELMNA | |
| SCHEMBL4188335 | 0.76 | ALDH1A1 (0.46) | MAPK1MCL1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1805430 | 0.75 | LMNA (0.69) | MAPK1MCL1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3816392 | 0.75 | LMNA (0.48) | MAPK1ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL4178799 | 0.73 | NPSR1 (0.47) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL30799600 | 0.71 | KDM4E (0.46) | MAPK1ALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |