Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.52 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433748 | 0.81 | HTR7 (0.76) | HTR7TP53OPRK1HTR6KDM4E | |
| SCHEMBL8979883 | 0.81 | HTR7 (0.82) | HTR7TP53OPRK1HTR6 | |
| SCHEMBL9434806 | 0.80 | PRMT5 (0.71) | TP53OPRK1PRMT5WDR77KDM4E | |
| Hydrochloric Acid SCHEMBL4230243 | 0.80 | HTR7 (0.80) | HTR7TP53OPRK1HTR6 | |
| SCHEMBL10035544 | 0.79 | HTR7 (0.82) | HTR7TP53OPRK1HTR6 | |
| SCHEMBL5741137 | 0.78 | HTR7 (1.00) | HTR7HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL2135298 | 0.78 | HTR7 (0.80) | HTR7TP53OPRK1HTR6 | |
| SCHEMBL8979897 | 0.78 | HTR7 (0.82) | HTR7TP53OPRK1HTR6 | |
| Hydrochloric Acid SCHEMBL4226132 | 0.77 | HTR7 (0.80) | HTR7TP53OPRK1HTR6 | |
| SCHEMBL8980040 | 0.77 | HTR7 (0.80) | HTR7OPRK1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294621-A | Thieno tetrahydropyridines useful as class III antiarrhythmic agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |