Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433749 | 0.87 | KDM4E (0.47) | POLBSMN1; SMN2KDM4EHSD17B10CASP1 | |
| SCHEMBL10961726 | 0.85 | POLB (0.54) | POLBSMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL9434438 | 0.83 | USP2 (0.46) | KDM4EHSD17B10CASP1TNKS2SIRT1 | |
| SCHEMBL9434185 | 0.83 | CACNA1B (0.52) | — | |
| SCHEMBL9434205 | 0.83 | CACNA1B (0.52) | — | |
| SCHEMBL9433784 | 0.83 | CYP11B1 (0.48) | POLBSMN1; SMN2KDM4EHSD17B10KMT2A | |
| SCHEMBL9433540 | 0.82 | KDM4E (0.45) | SMN1; SMN2KDM4EHSD17B10CASP1KMT2A | |
| SCHEMBL9433568 | 0.81 | KDM4E (0.44) | SMN1; SMN2KDM4EHSD17B10CASP1KMT2A | |
| SCHEMBL9433813 | 0.80 | KDM4E (0.43) | SMN1; SMN2KDM4EHSD17B10CASP1KMT2A | |
| SCHEMBL9434790 | 0.80 | KDM4E (0.43) | SMN1; SMN2KDM4EHSD17B10CASP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |