Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 4/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433956 | 0.86 | BACE1 (0.48) | STING1BACE1ALDH1A1GAAHPGD | |
| SCHEMBL9433877 | 0.81 | IKBKB (0.58) | STING1IKBKBSLC9A1BACE1ALDH1A1 | |
| SCHEMBL9434315 | 0.80 | MAPK1 (0.51) | STING1IKBKBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7218005 | 0.71 | KDM4E (0.60) | STING1IKBKBBACE1ALDH1A1GAA | |
| SCHEMBL26049804 | 0.71 | EDNRA (0.50) | STING1BACE1ALDH1A1GAAHPGD | |
| SCHEMBL11101251 | 0.70 | BACE1 (0.54) | BACE1ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9434117 | 0.69 | ALDH1A1 (0.49) | STING1ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL22908903 | 0.68 | STING1 (0.47) | STING1BACE1MAPK1HDAC3HDAC4 | |
| SCHEMBL9024186 | 0.68 | STING1 (0.42) | STING1IKBKBSLC9A1ALDH1A1GAA | |
| SCHEMBL1030218 | 0.68 | CA12 (0.65) | ALDH1A1HPGDHSD17B10L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350748-A | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion | WARNER-LAMBERT COMPANY (US) | 1994-09-27 | — | — | US | disclosed |