Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | MYB | P10242 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434111 | 0.88 | CACNA1F (0.47) | MAPTALDH1A1POLBMAPK1CACNA1F | |
| SCHEMBL9433733 | 0.83 | CACNA1B (0.55) | MAPTALDH1A1POLBMAPK1CACNA1F | |
| SCHEMBL9434587 | 0.83 | CACNA1F (0.53) | MAPTALDH1A1POLBMAPK1CACNA1F | |
| SCHEMBL9433325 | 0.82 | LMNA (0.57) | MAPTALDH1A1POLBMAPK1CACNA1F | |
| Hydrochloric Acid SCHEMBL9434672 | 0.82 | CACNA1B (0.54) | MAPTALDH1A1POLBMAPK1CACNA1F | |
| SCHEMBL9434647 | 0.82 | CACNA1F (0.52) | MAPTALDH1A1POLBMAPK1CACNA1F | |
| SCHEMBL9433933 | 0.81 | MAPT (0.46) | MAPTALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL9434141 | 0.81 | KDM4E (0.54) | MAPTALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL9434383 | 0.80 | MAPT (0.64) | MAPTPOLBMAPK1SMN1; SMN2CACNA1F | |
| SCHEMBL9433977 | 0.80 | CACNA1C (0.59) | MAPTPOLBMAPK1CACNA1FCACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |