Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 3/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434601 | 0.83 | CACNA1F (0.52) | KDM4EALDH1A1MAPTKMT2AADORA3 | |
| SCHEMBL9433980 | 0.83 | CACNA1F (0.52) | MAPTKMT2AADORA3CACNA1FCACNA1D | |
| SCHEMBL9434657 | 0.82 | CACNA1F (0.51) | MAPTKMT2AADORA3CACNA1FCACNA1D | |
| SCHEMBL9434138 | 0.81 | MAPT (0.46) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL9434369 | 0.81 | MAPT (0.63) | MAPTKMT2AADORA3CACNA1FCACNA1D | |
| SCHEMBL9434484 | 0.81 | LMNA (0.55) | ALDH1A1MAPTKMT2AHTTADORA3 | |
| SCHEMBL9434367 | 0.80 | CACNA1F (0.44) | MAPTKMT2AADORA3CACNA1FCACNA1D | |
| SCHEMBL9433965 | 0.80 | CACNA1F (0.58) | MAPTKMT2AADORA3CACNA1FCACNA1D | |
| SCHEMBL9433883 | 0.79 | CACNA1F (0.71) | MAPTKMT2AADORA3CACNA1FCACNA1D | |
| SCHEMBL9434781 | 0.79 | MEN1 (0.63) | KDM4EALDH1A1GAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |