Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432929 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9432882 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1HTTPARP1KMT2ASMN1; SMN2 | |
| SCHEMBL9433063 | 0.81 | HTT (0.67) | ALDH1A1HTTPARP1MEN1KMT2A | |
| SCHEMBL31091352 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9433250 | 0.78 | HTT (0.48) | ALDH1A1HTTPARP1KMT2ASMN1; SMN2 | |
| SCHEMBL9433022 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HTTPARP1MEN1KMT2A | |
| SCHEMBL9432691 | 0.74 | HTT (0.44) | ALDH1A1HTTPARP1KMT2AL3MBTL1 | |
| SCHEMBL9432755 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HTTPARP1MEN1KMT2A | |
| SCHEMBL9432819 | 0.73 | FAAH (0.41) | HTTPARP1AXLL3MBTL1LMNA | |
| SCHEMBL7696381 | 0.72 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4235960-A | — | — | None | — | — | JP | disclosed |
| US-5288776-A | Heat resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| JP-H04235960-A | SUBSTITUTED PYRROLE AS STABILIZER FOR CHLORINATED POLYMER | CIBA GEIGY AG | 1992-08-25 | — | — | JP | disclosed |
| EP-0465405-A2 | Substituted pyrroles used as stabilisers for chlorine containing polymers | CIBA-GEIGY AG (CH) | 1992-01-08 | — | — | EP | disclosed |