Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 10/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766887 | 0.90 | MTOR (0.35) | MTORPIK3CAHSD17B10 | |
| SCHEMBL9434621 | 0.88 | RARB (0.36) | NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9433781 | 0.88 | KDM4C (0.36) | KDM4CSLC6A4MTORPIK3CANPC1 | |
| SCHEMBL9434234 | 0.87 | RARB (0.40) | NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9433010 | 0.86 | NPC1 (0.34) | KDM4CMTORPIK3CANPC1RAB9A | |
| SCHEMBL8766253 | 0.78 | RARB (0.38) | MTORPIK3CANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8766807 | 0.78 | RAB9A (0.39) | MTORPIK3CANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8766819 | 0.77 | RARB (0.43) | NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9433261 | 0.76 | RAB9A (0.47) | NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL8767583 | 0.75 | NPC1 (0.39) | MTORPIK3CANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372746-A | Fluoro-substituted tolane compounds and liquid crystalline mixtures containing same | HOFFMANN-LA ROCHE INC. (US) | 1994-12-13 | — | — | US | disclosed |