Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.47 |
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433608 | 0.97 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL9433719 | 0.94 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL8766676 | 0.90 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL9433781 | 0.89 | KDM4C (0.36) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL8766722 | 0.87 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL9434621 | 0.87 | RARB (0.36) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL9434234 | 0.84 | RARB (0.40) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL8766342 | 0.83 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL9030549 | 0.81 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL9433010 | 0.80 | NPC1 (0.34) | RAB9ASMN1; SMN2NPC1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372746-A | Fluoro-substituted tolane compounds and liquid crystalline mixtures containing same | HOFFMANN-LA ROCHE INC. (US) | 1994-12-13 | — | — | US | disclosed |