Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434846 | 0.88 | ALDH1A1 (0.43) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 | |
| SCHEMBL9434702 | 0.87 | KDM4E (0.61) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 | |
| SCHEMBL9434006 | 0.87 | KDM4E (0.46) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 | |
| SCHEMBL9434410 | 0.83 | CACNA1B (0.45) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 | |
| SCHEMBL9434633 | 0.83 | CACNA1B (0.59) | CACNA1B | |
| SCHEMBL9434080 | 0.82 | CACNA1B (0.48) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 | |
| SCHEMBL9433540 | 0.81 | KDM4E (0.45) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 | |
| SCHEMBL9434752 | 0.81 | KDM4E (0.45) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 | |
| SCHEMBL9433666 | 0.80 | CACNA1B (0.50) | KDM4EHSD17B10CACNA1BCASP1 | |
| SCHEMBL9433568 | 0.80 | KDM4E (0.44) | KDM4EHSD17B10CACNA1BCASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276150-A | Vasodilators, anticoagulants, calcium channel blockers | FUJIREBIO INC. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |