SCHEMBL9434749

SCHEMBL9434749

CCC(=O)/C(CC(=O)O)=N\OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.36
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
TSHR P16473 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899329 0.82 TRPA1 (0.37) FFAR3TRPA1
SCHEMBL9899327 0.82 TRPA1 (0.37) FFAR3TRPA1
SCHEMBL8520258 0.73
SCHEMBL8500776 0.72 ALDH1A1 (0.31)
SCHEMBL20771269 0.71 TDP1 (0.36) FFAR3TRPA1
SCHEMBL7231561 0.71 TDP1 (0.36) FFAR3TRPA1
Bicarbonate SCHEMBL9434753 0.70 FFAR3 (0.33) FFAR3
SCHEMBL14252537 0.70 FFAR3 (0.33) FFAR3
SCHEMBL2048002 0.69 TRPA1 (0.42) TRPA1
SCHEMBL2048005 0.69 TRPA1 (0.42) TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994021620-A1 AMINO-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS RENIN INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed