Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783537 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDATMNOS3NOS1 | |
| SCHEMBL4465857 | 0.75 | ALDH1A1 (0.40) | ALDH1A1ATMNOS3NOS1NOS2 | |
| SCHEMBL31030757 | 0.72 | PDE4A (0.45) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7832996 | 0.71 | SCARB1 (0.37) | DAPK3ALDH1A1S1PR1HPGDMEN1 | |
| SCHEMBL1338840 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HPGDATMTSHRMEN1 | |
| SCHEMBL6648616 | 0.70 | ALDH1A1 (0.39) | ALDH1A1S1PR1HPGDATMTSHR | |
| SCHEMBL13934519 | 0.69 | MEN1 (0.45) | ALDH1A1HPGDMEN1LMNAKMT2A | |
| SCHEMBL34460862 | 0.69 | ALDH1A1 (0.41) | ALDH1A1ATMNOS3NOS1NOS2 | |
| SCHEMBL31158574 | 0.69 | ALDH1A1 (0.41) | ALDH1A1ATMNOS3NOS1NOS2 | |
| SCHEMBL4303038 | 0.69 | ALDH1A1 (0.55) | DAPK3ALDH1A1S1PR1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994015920-A1 | BENZANILIDE DERIVATIVES AS 5-HT1D-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |