Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435018 | 0.85 | — | — | |
| SCHEMBL8148021 | 0.82 | ESR1 (0.38) | MAPTPOLBMEN1KMT2A | |
| SCHEMBL8146059 | 0.82 | TP53 (0.35) | MEN1KMT2AALOX15 | |
| SCHEMBL8141067 | 0.82 | — | — | |
| SCHEMBL8147980 | 0.82 | — | — | |
| SCHEMBL8155848 | 0.81 | PDE1C (0.36) | MAPTMEN1KMT2A | |
| SCHEMBL8153451 | 0.81 | — | — | |
| SCHEMBL8154899 | 0.75 | MAOB (0.44) | MAPTPOLBMEN1KMT2A | |
| SCHEMBL9434365 | 0.74 | FGB (0.42) | MAPTKMT2ATSHRKDM4E | |
| SCHEMBL9434368 | 0.74 | SMN1; SMN2 (0.36) | MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002483-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |