Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259177 | 0.86 | TDP1 (0.78) | TDP1CYP1A2CYP2C9KMT2AKCNK3 | |
| SCHEMBL31006487 | 0.84 | PTGS2 (0.67) | TDP1CYP3A4CYP2C19KMT2AGAA | |
| SCHEMBL28871781 | 0.84 | PTGS2 (0.67) | TDP1CYP3A4CYP2C19KMT2AGAA | |
| SCHEMBL3114250 | 0.84 | KCNK3 (0.63) | KMT2AGAAKCNK3LMNASMN1; SMN2 | |
| SCHEMBL1827711 | 0.82 | SMN1; SMN2 (0.70) | TDP1KMT2AGAAKCNK3LMNA | |
| SCHEMBL11832072 | 0.82 | PTGS2 (0.68) | CYP3A4CYP2C19CYP2C9GAAKCNK3 | |
| SCHEMBL31006498 | 0.82 | PTGS2 (0.68) | CYP3A4CYP2C19CYP2C9GAAKCNK3 | |
| SCHEMBL16299040 | 0.80 | KMT2A (0.65) | TDP1CYP3A4CYP2C19KMT2AGAA | |
| SCHEMBL31661935 | 0.77 | BRAF (0.79) | TDP1KMT2AKCNK3LMNAHIF1A | |
| SCHEMBL12979 | 0.77 | BRAF (0.79) | TDP1KMT2AKCNK3LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994024109-A1 | INDAZOLE DERIVATIVES AND ANTIVIRAL DRUGS THAT CONTAIN THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1994-10-27 | — | — | WO | disclosed |