SCHEMBL31661935

SCHEMBL31661935

Cc1cccc(C(=O)Nc2cccnc2)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRAF P15056 1/20 0.79
CSF1R P07333 1/20 0.76
NAMPT P43490 3/20 0.71
NT5E P21589 1/20 0.71
KCNK3 O14649 3/20 0.70
KCNK9 Q9NPC2 3/20 0.70
LMNA P02545 3/20 0.69
KCNH2 Q12809 1/20 0.69
HIF1A Q16665 1/20 0.69
ALDH1A1 P00352 1/20 0.69
NPC1 O15118 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
RXFP1 Q9HBX9 1/20 0.65
MAPT P10636 2/20 0.64
POLB P06746 1/20 0.64
GALR2 O43603 1/20 0.63
HPGD P15428 1/20 0.63
RECQL P46063 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12979 1.00 BRAF (0.79) BRAFCSF1RNAMPTNT5EKCNK3
SCHEMBL12411961 0.91 BRAF (0.71) BRAFCSF1RNAMPTNT5EKCNK3
SCHEMBL30533390 0.89 LMNA (0.81) NAMPTKCNK3LMNAHIF1AALDH1A1
SCHEMBL3937779 0.89 BRAF (1.00) BRAFCSF1RKCNK3KCNK9
SCHEMBL259177 0.88 TDP1 (0.78) BRAFCSF1RNAMPTKCNK3KCNK9
SCHEMBL3935559 0.87 BRAF (0.80) BRAFCSF1RKCNK3KCNK9
SCHEMBL3941840 0.87 CSF1R (1.00) BRAFCSF1RKCNK3KCNK9NPC1
SCHEMBL790322 0.85 NAMPT (0.71) BRAFCSF1RNAMPTLMNAHIF1A
SCHEMBL14210406 0.85 SIRT2 (0.72) BRAFCSF1RNAMPTLMNAHIF1A
SCHEMBL19662798 0.85 NT5E (0.70) BRAFCSF1RNT5EKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151311-A1 NICOTINAMIDE DERIVATIVES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-07-17 WO disclosed