Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16346609 | 0.85 | RAB9A (0.57) | MAPTALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL1764528 | 0.84 | GAA (0.64) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL1765084 | 0.80 | MAPT (0.64) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL8256648 | 0.79 | GAA (0.58) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL10242015 | 0.79 | GAA (0.78) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL1764592 | 0.78 | RAB9A (0.61) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL3346281 | 0.76 | RECQL (0.61) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL22051446 | 0.76 | MAPT (0.55) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL4821852 | 0.76 | ALDH1A1 (0.68) | MAPTGAARECQLALDH1A1KDM4E | |
| SCHEMBL1765099 | 0.76 | ALDH1A1 (0.58) | MAPTGAARECQLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994015920-A1 | BENZANILIDE DERIVATIVES AS 5-HT1D-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |