Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.61 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | KLK8 | O60259 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK2 | P20151 | 1/20 | 0.41 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710341 | 0.84 | ITGB3 (0.67) | ITGB3ITGA2BCTSGCMA1PRSS1 | |
| SCHEMBL9100789 | 0.78 | ITGB3 (0.63) | ITGB3ITGA2BCTSGCMA1PRSS1 | |
| SCHEMBL9435428 | 0.78 | ITGB3 (0.60) | ITGB3ITGA2BCTSGCMA1HDAC1 | |
| SCHEMBL7431042 | 0.77 | ITGB3 (0.70) | ITGB3ITGA2BCTSGCMA1PRSS1 | |
| SCHEMBL9710588 | 0.77 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL7387875 | 0.77 | ITGB3 (0.76) | ITGB3ITGA2BCTSGCMA1PRSS1 | |
| SCHEMBL7390380 | 0.77 | ITGB3 (0.64) | ITGB3ITGA2BCTSGPRSS1F2 | |
| SCHEMBL7721971 | 0.76 | ITGB3 (0.58) | ITGB3ITGA2BCTSGCMA1PRSS1 | |
| SCHEMBL7381387 | 0.76 | ITGB3 (0.84) | ITGB3ITGA2BF10 | |
| SCHEMBL7381799 | 0.76 | ITGB3 (1.00) | ITGB3ITGA2BCTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574545-B1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1994-11-30 | — | — | EP | disclosed |