Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423622 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL7049219 | 0.93 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL11334284 | 0.91 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9956852 | 0.86 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL4325251 | 0.85 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL29731549 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9308000 | 0.81 | POLB (0.47) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL10897324 | 0.80 | USP2 (0.46) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL9039622 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL19243087 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6340681-A | — | — | None | — | — | JP | disclosed |
| JP-H06340681-A | PHOSPHORIC ACID (PHOSPHONIC ACID) DERIVATIVES | BAYER AG | 1994-12-13 | — | — | JP | disclosed |