Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 9/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435539 | 1.00 | CACNA1G (0.57) | CACNA1GKCNH2RECQLTSHRGAA | |
| SCHEMBL9098357 | 0.90 | TSHR (0.52) | CACNA1GKCNH2TSHRMAPT | |
| SCHEMBL9098366 | 0.90 | TSHR (0.52) | CACNA1GKCNH2TSHRMAPT | |
| SCHEMBL9098349 | 0.90 | TSHR (0.52) | CACNA1GKCNH2TSHRMAPT | |
| SCHEMBL9435818 | 0.89 | CACNA1G (0.58) | CACNA1GKCNH2TSHRGAAUSP2 | |
| SCHEMBL9435813 | 0.89 | CACNA1G (0.58) | CACNA1GKCNH2TSHRGAAUSP2 | |
| SCHEMBL9435578 | 0.89 | TSHR (0.54) | CACNA1GKCNH2TSHRMAPT | |
| SCHEMBL9435568 | 0.89 | TSHR (0.54) | CACNA1GKCNH2TSHRMAPT | |
| SCHEMBL9435768 | 0.85 | TSHR (0.51) | CACNA1GKCNH2TSHRMAPT | |
| SCHEMBL9435774 | 0.85 | TSHR (0.51) | CACNA1GKCNH2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371088-A | 1-aryl-4-piperazinylcyclohexanecarbonitriles, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |