Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376312 | 0.81 | GAA (0.52) | AKR1B1ALDH1A1TDP1MEN1RAB9A | |
| SCHEMBL22494208 | 0.81 | — | — | |
| SCHEMBL8982451 | 0.78 | AKR1B1 (0.50) | HTR6AKR1B1ALDH1A1KDM4ECA1 | |
| SCHEMBL9492468 | 0.74 | CA1 (0.42) | ALDH1A1TDP1MEN1RAB9AKMT2A | |
| SCHEMBL6924070 | 0.73 | HTR6 (0.59) | HTR6AKR1B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL8074581 | 0.72 | HTR6 (0.65) | HTR6AKR1B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL27459397 | 0.69 | HTR6 (0.54) | HTR6AKR1B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL9618200 | 0.69 | KEAP1 (0.53) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL1350575 | 0.69 | TSHR (0.50) | ALDH1A1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL3474994 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6340638-A | — | — | None | — | — | JP | disclosed |
| JP-6340638-A | — | — | None | — | — | JP | disclosed |
| JP-H06340638-A | PRODUCTION OF 3-(PHENYLSULFONYL)-1,2,4-TRIAZOLES | NIPPON PEROXIDE CO LTD | 1994-12-13 | — | — | JP | disclosed |
| JP-H06340638-A | PRODUCTION OF 3-(PHENYLSULFONYL)-1,2,4-TRIAZOLES | NIPPON PEROXIDE CO LTD | 1994-12-13 | — | — | JP | disclosed |