Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436083 | 1.00 | HRH4 (0.31) | HRH4ALDH1A1 | |
| SCHEMBL10567402 | 0.84 | HRH4 (0.31) | HRH4ALDH1A1 | |
| SCHEMBL9777093 | 0.82 | HRH4 (0.32) | HRH4ALDH1A1 | |
| SCHEMBL9777091 | 0.82 | HRH4 (0.32) | HRH4ALDH1A1 | |
| SCHEMBL11215888 | 0.80 | BCHE (0.32) | HRH4ALDH1A1 | |
| SCHEMBL10999302 | 0.80 | HRH4 (0.31) | HRH4ALDH1A1 | |
| SCHEMBL9809754 | 0.80 | BCHE (0.32) | HRH4ALDH1A1 | |
| SCHEMBL9809757 | 0.80 | BCHE (0.32) | HRH4ALDH1A1 | |
| SCHEMBL10999299 | 0.80 | HRH4 (0.31) | HRH4ALDH1A1 | |
| SCHEMBL11801557 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279161-B1 | A process for the preparation of cimetidine | LEK TOVARNA FARMACEVTSKIH (SI) | 1994-01-05 | — | — | EP | claimed |
| US-4855439-A | Process for the preparation of cimetidine | LEK (YU) | 1989-08-08 | — | — | US | claimed |
| US-4200761-A | Process for preparing N-cyano-N'methyl-N\"-{2-[(4-methyl-5-imidazolyl)-methylthio]-ethyl} guanidine | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1980-04-29 | — | — | US | claimed |
| EP-0279161-B1 | A process for the preparation of cimetidine | LEK TOVARNA FARMACEVTSKIH (SI) | 1994-01-05 | — | — | EP | disclosed |
| US-4855439-A | Process for the preparation of cimetidine | LEK (YU) | 1989-08-08 | — | — | US | disclosed |
| US-4855439-A | Process for the preparation of cimetidine | LEK (YU) | 1989-08-08 | — | — | US | disclosed |
| US-4200761-A | Process for preparing N-cyano-N'methyl-N\"-{2-[(4-methyl-5-imidazolyl)-methylthio]-ethyl} guanidine | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1980-04-29 | — | — | US | disclosed |
| US-4200761-A | Process for preparing N-cyano-N'methyl-N\"-{2-[(4-methyl-5-imidazolyl)-methylthio]-ethyl} guanidine | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1980-04-29 | — | — | US | disclosed |