Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215888 | 1.00 | BCHE (0.32) | BCHEACHEHRH4ALDH1A1 | |
| SCHEMBL9809754 | 1.00 | BCHE (0.32) | BCHEACHEHRH4ALDH1A1 | |
| SCHEMBL11527369 | 0.89 | HRH4 (0.35) | BCHEACHEHRH4 | |
| SCHEMBL11527367 | 0.89 | HRH4 (0.35) | BCHEACHEHRH4 | |
| SCHEMBL9777093 | 0.82 | HRH4 (0.32) | HRH4ALDH1A1 | |
| SCHEMBL9777091 | 0.82 | HRH4 (0.32) | HRH4ALDH1A1 | |
| SCHEMBL11527452 | 0.81 | HRH4 (0.47) | BCHEACHEHRH4 | |
| SCHEMBL11527451 | 0.81 | HRH4 (0.47) | BCHEACHEHRH4 | |
| SCHEMBL6351490 | 0.80 | — | — | |
| SCHEMBL10567402 | 0.80 | HRH4 (0.31) | HRH4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830896-B | Preparation method of cimetidine | 盐城凯利药业有限公司 | 2021-08-17 | — | — | CN | claimed |
| EP-0046635-B1 | PROCESS FOR THE PREPARATION OF CIMETIDINE | ORION-YHTYMÄ OY (FI) | 1985-07-03 | — | — | EP | claimed |
| EP-0046635-A1 | Process for the preparation of cimetidine | ORION-YHTYMÄ OY (FI) | 1982-03-03 | — | — | EP | claimed |
| JP-57120573-A | — | — | None | — | — | JP | disclosed |
| JP-60092257-A | — | — | None | — | — | JP | disclosed |
| JP-57091978-A | — | — | None | — | — | JP | disclosed |
| JP-63045266-A | — | — | None | — | — | JP | disclosed |
| JP-59190973-A | — | — | None | — | — | JP | disclosed |
| JP-59128375-A | — | — | None | — | — | JP | disclosed |
| JP-58188855-A | — | — | None | — | — | JP | disclosed |
| CN-115960048-B | Cimetidine Process for the preparation of guanidine | 常州安迪沃克医药科技有限公司 | 2025-01-24 | — | — | CN | disclosed |
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4276421-A | Cyano-guanidine geometrical isomers | SOCIETE DE RECHERCHES ET DE SYNTHESES ORGANIQUES S.A. (CH) | 1981-06-30 | — | — | US | disclosed |
| US-4267337-A | Imidazolemethylphosphonium salts | SK&F LAB CO. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4255440-A | ANTIALLERGENS, ANTIULCER AGENTS | ALLEN & HANBURYS LIMITED (GB) | 1981-03-10 | — | — | US | disclosed |
| US-4215217-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4171325-A | Chemical process | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-16 | — | — | US | disclosed |
| US-4169855-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | Allen & Hansbury, Limited (GB) | 1979-10-02 | — | — | US | disclosed |
| US-4128658-A | HISTAMINE ANTAGONISTS | ALLEN & HANBURYS LIMITED (GB) | 1978-12-05 | — | — | US | disclosed |
| US-4119781-A | Process for preparing 4-substituted imidazole compounds | SK&F LAB CO. (US) | 1978-10-10 | — | — | US | disclosed |