Fluorene

Fluorene

SCHEMBL9435671

F.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.65
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
KDM4E B2RXH2 2/20 0.58
MAPT P10636 2/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
CES1 P23141 2/20 0.52
BCHE P06276 1/20 0.52
SRD5A2 P31213 1/20 0.50
PLK4 O00444 1/20 0.48
DAPK3 O43293 1/20 0.48
PIM1 P11309 1/20 0.48
PDGFRA P16234 1/20 0.48
LTK P29376 1/20 0.48
MAP2K2 P36507 1/20 0.48
FLT3 P36888 1/20 0.48
MAPK8 P45983 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL27489769 1.00 MAOA (0.65) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL27916234 0.97 MAOA (0.62) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL545861 0.97 MAOA (0.68) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL29478468 0.97 MAOA (0.68) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL31388525 0.97 MAOA (0.68) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL8180 0.97 MAOA (0.68) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL29355380 0.97 MAOA (0.68) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL10626727 0.93 MAOA (0.65) MAOANPC1RAB9ASMN1; SMN2KDM4E
Fluorene SCHEMBL8378972 0.93 MAOA (0.65) MAOANPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL6481957 0.93 MAOA (0.65) MAOANPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6342655-A None JP disclosed
WO-2020063913-A1 PREPARATION METHOD FOR SCANDIUM FLUORIDE 中国恩菲工程技术有限公司 2020-04-02 WO disclosed
CN-105669358-A Method for fluoridizing multi-substitution fluorene derivatives 中国药科大学 2016-06-15 CN disclosed
CN-105541590-A Synthetic method of fluorene fluoride compound JIANG HUILAN 2016-05-04 CN disclosed
CN-105541590-A Synthetic method of fluorene fluoride compound JIANG HUILAN 2016-05-04 CN disclosed
JP-H06342655-A ELECTRODE AND BATTERY PROVIDED THEREWITH OSAKA GAS CO LTD 1994-12-13 JP disclosed