Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791694 | 0.92 | GAA (0.60) | GAATSHRRAB9ANPSR1NPC1 | |
| SCHEMBL3302544 | 0.90 | POLB (0.69) | GAATSHRRAB9ANPSR1NPC1 | |
| SCHEMBL10595693 | 0.86 | GAA (0.61) | GAATSHRRAB9ANPSR1PKM | |
| SCHEMBL11324057 | 0.85 | GAA (0.56) | GAATSHRRAB9ANPSR1NPC1 | |
| SCHEMBL10767909 | 0.84 | TSHR (0.68) | GAATSHRRAB9ANPSR1NPC1 | |
| SCHEMBL12994648 | 0.83 | POLB (0.66) | GAATSHRRAB9ANPSR1NPC1 | |
| SCHEMBL6710643 | 0.81 | POLB (0.59) | GAATSHRRAB9ANPC1TP53 | |
| SCHEMBL13060491 | 0.81 | RAB9A (0.62) | GAATSHRRAB9ANPC1TP53 | |
| SCHEMBL10771088 | 0.81 | RAB9A (0.64) | GAARAB9ANPC1TP53POLB | |
| SCHEMBL8616896 | 0.81 | POLB (0.59) | GAATSHRRAB9ANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283362-A | Reacting with an amine, terminating the reaction before the formation of by-product | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1994-02-01 | — | — | US | disclosed |
| EP-0239170-A1 | Stabilized lactam polymerization solutions | DSM RIM NYLON V.O.F (NL) | 1987-09-30 | — | — | EP | disclosed |
| US-4694039-A | Stabilized lactam polymerization solutions | DSM RIM NYLON V.O.F. (NL) | 1987-09-15 | — | — | US | disclosed |