Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302544 | 0.90 | POLB (0.69) | POLBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL10771088 | 0.89 | RAB9A (0.64) | POLBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL12994648 | 0.83 | POLB (0.66) | POLBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL31179955 | 0.83 | HDAC6 (0.56) | POLBRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9435704 | 0.81 | GAA (0.68) | POLBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL6710643 | 0.81 | POLB (0.59) | POLBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL13060491 | 0.81 | RAB9A (0.62) | POLBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL13666660 | 0.81 | RAB9A (0.59) | POLBRAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL100560 | 0.81 | TSHR (0.63) | POLBTSHRSAE1UBA2CA12 | |
| SCHEMBL7095263 | 0.81 | MEN1 (0.66) | POLBRAB9ASMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10338290-B2 | Cellulose ester film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2019-07-02 | — | — | US | disclosed |
| US-10040754-B2 | Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2018-08-07 | — | — | US | disclosed |
| US-20160370522-A1 | CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-12-22 | — | — | US | disclosed |
| US-20150361036-A1 | CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2015-12-17 | — | — | US | disclosed |
| EP-0533954-B1 | DIAMINOUREA COMPOUND AND PRODUCTION THEREOF, AND HIGHLY HEAT-RESISTANT POLYURETHANE-UREA AND PRODUCTION THEREOF | ASAHI CHEMICAL IND (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5576410-A | REACTION OF DIISOCYANATE, DIOL AND DIAMINO UREA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1996-11-19 | — | — | US | disclosed |
| US-5414118-A | Reacting a tetraalkyl methanediphenylenediurea with an alkylenediamine | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1995-05-09 | — | — | US | disclosed |
| US-5241118-A | Reacting nitroarene with carbon monoxide | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0533954-A1 | DIAMINOUREA COMPOUND AND PRODUCTION THEREOF, AND HIGHLY HEAT-RESISTANT POLYURETHANE-UREA AND PRODUCTION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040754-B2 | Cellulose acylate film, novel compound, polarizing plate and liquid crystal display device | NR1D1, NR1H2, NR1D2 | POLB 4180/4885RAB9A 4375/4885SMN1; SMN2 3280/4885 |
| US-20150361036-A1 | CELLULOSE ACYLATE FILM, NOVEL COMPOUND, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE | NR1D1, NR1H2, NR1D2 | POLB 4180/4885RAB9A 4375/4885SMN1; SMN2 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.