SCHEMBL9435759

SCHEMBL9435759

C=C(C)C(=O)OCC(C)O.C=CC=CC=CC#N

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylonitrile SCHEMBL6658905 0.85 TSHR (0.56) TSHRTHRB
SCHEMBL11545868 0.81 TSHR (0.39) TSHRTHRB
SCHEMBL9562491 0.79 TSHR (0.60) TSHRTHRB
SCHEMBL9250386 0.78 ALDH1A1 (0.50) TSHR
SCHEMBL3273928 0.78 TSHR (0.58) TSHRTHRB
SCHEMBL9695772 0.77 TSHR (0.72) TSHRTHRB
SCHEMBL19017 0.77 TSHR (0.72) TSHRTHRB
SCHEMBL11667567 0.77 TSHR (0.53) TSHRTHRB
Acrylic Acid SCHEMBL2354185 0.76 TSHR (0.60) TSHRTHRB
Ammonia Solution, Strong SCHEMBL28645738 0.75 TSHR (0.69) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5362810-A Toughness, weathering BAYER AKTIENGESELLSCHAFT 1994-11-08 US disclosed