Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylonitrile SCHEMBL11546320 | 0.83 | THRB (0.43) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylonitrile SCHEMBL9562747 | 0.83 | THRB (0.46) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL8056534 | 0.82 | TSHR (0.61) | TSHRTHRBALDH1A1 | |
| SCHEMBL9435759 | 0.81 | TSHR (0.45) | TSHRTHRB | |
| SCHEMBL9250386 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL8057172 | 0.79 | THRB (0.40) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Butadiene SCHEMBL27878557 | 0.79 | THRB (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL441192 | 0.78 | POLB (0.38) | ALDH1A1POLBAPEX1HTTTDP1 | |
| Cyanate SCHEMBL2803013 | 0.78 | THRB (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Acrylonitrile SCHEMBL23071585 | 0.78 | ALDH1A1 (0.47) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152308-A | SILICEOUS FILLED VULCANIZATES | POLYSAR LIMITED (CA) | 1979-05-01 | — | — | US | disclosed |
| US-4150014-A | HYDROXYL HYDROCARBYL POLYMER, AMINE, SHEARING | POLYSAR LIMITED (CA) | 1979-04-17 | — | — | US | disclosed |