Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 1.00 |
| ▸ | CA12 | O43570 | 13/20 | 1.00 |
| ▸ | CA9 | Q16790 | 13/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 1.00 |
| ▸ | CA2 | P00918 | 10/20 | 1.00 |
| ▸ | CA1 | P00915 | 7/20 | 0.90 |
| ▸ | MMP8 | P22894 | 3/20 | 0.90 |
| ▸ | MMP1 | P03956 | 2/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | MMP7 | P09237 | 1/20 | 0.61 |
| ▸ | MMP14 | P50281 | 1/20 | 0.61 |
| ▸ | FLT1 | P17948 | 3/20 | 0.54 |
| ▸ | FLT4 | P35916 | 3/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811835 | 0.82 | MMP2 (1.00) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL13111454 | 0.82 | MMP2 (0.70) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL9811882 | 0.81 | MMP2 (1.00) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL9811918 | 0.81 | CA12 (0.69) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL7409476 | 0.79 | MMP2 (0.74) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL7409478 | 0.79 | MMP2 (0.74) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL11767663 | 0.79 | MMP2 (0.65) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL7648565 | 0.77 | MMP2 (1.00) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL7648573 | 0.77 | MMP2 (1.00) | MMP2CA12CA9CA14CA2 | |
| SCHEMBL10910171 | 0.76 | CA2 (0.61) | MMP2CA12CA9CA14CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586521-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021355-A1 | CALCIUM, TRACE MINERAL, VITAMIN D AND DRUG THERAPY COMBINATIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-12-10 | — | — | WO | disclosed |
| EP-0243173-B1 | NEW DIPHOSPHONIC ACID COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |
| US-4963536-A | INHIBIT BONE RESORPTION | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| US-4857513-A | Diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISIWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0243173-A2 | New diphosphonic acid compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |